Alzheimer’s disease is a degenerative ailment that impacts the brain. It affects nearly 50 million people around the globe with more than 5 million Americans suffering from it too. The condition is characterized by memory loss, lack of concentration, hallucinations, and more.
Unfortunately, however, there is no cure for it so far. Specialists concoct a treatment plan that helps manage symptoms such as anxiety and sleeplessness linked to the condition. But there is no way, so far, to reverse the damaged brain.
Typically, two harmful proteins, the tau protein and beta-amyloid are blamed as the cause for Alzheimer’s disease. However, recent findings reveal that leaky capillaries may be responsible for all the brain damage.
These findings have been made by researchers from the University of Southern California (USC) in Los Angeles and their results have been published in the journal Nature Medicine.
The study lasted for a total of five years and had a participant pool of 161 older adults. The researchers noted that people with severe memory issues showcase leaky blood capillaries in the brain.
This connection persisted irrespective of the presence of the toxic proteins in the brain. Essentially, the matter boils down to the blood brain barrier. This is a structure which is formed by the cells that make blood vessels.
In a healthy brain, the blood brain barrier is intact with the cells fitting together. This stops any unwanted and harmful substances from crossing the barrier into the brain zone. In some aging brains though, the junction between the cells gets loose.
When that happens, the blood vessels start leaking, which is why the brain doesn’t receive the needed nutrients. On top of that, toxic proteins can also easily cross over the brain. All this culminates in brain damage.
Therefore, this study sheds light on a new matter for helping find out a possible treatment plan for Alzheimer’s disease.